More than 80% of premature infants cared for in the intensive care nursery receive at least 1 blood transfusion. Multiple blood draws causing anemia and the need for increasing oxygen-carrying capacity are the 2 main reasons for infants to receive a blood transfusion. Intravascular fluid overload posttransfusion is a concern. MeSH terms. Blood Transfusion/adverse effects*; Blood Volume*; Diuretics/administration & dosage*; Furosemide/administration & dosage*; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Water-Electrolyte Imbalance/prevention & control*.
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Objectives: This review aimed to determine if the prophylactic administration of loop diuretics (furosemide, bumetanide, ethacrynic acid, or torsemide) provides a therapeutic advantage (that is, a favourable risk benefit ratio) in adults and children who are recipients of any blood product transfusion versus placebo. Pulmonary capillary 'wedge' pressures (PCWP) were measured in 20 adult cases of chronic severe anemia (CSA) before and after transfusion of ml of whole blood at a rate of 5 ml/min. The cases were randomly divided into 2 groups of 10 cases each. Group II also received 40 mg of furosemide immediately before the.
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