The maximum recommended dosage of ARICEPT in patients with mild to moderate Alzheimer's disease is 10 mg per day. A dose of 10 mg should not be on a daily dose of 5 mg for 4 to 6 weeks. A dose of 23 mg per day should not be administered until patients have been on a daily dose of 10 mg for at least 3 months. -Maintenance dose: 10 mg orally once a day, after the patient has been on an initial dose of 5 mg once a day for 4 to 6 weeks. Moderate to severe Alzheimer's disease: Maintenance dose: 23 mg orally once a day, after the patient has been on a dose of 10 mg once a day for at least 3 months. Comments: A higher dose of
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Specifically, in a controlled trial that compared a dose of 23 mg/day to 10 mg/day in patients who had been treated with donepezil 10 mg/day for at least three months, the incidence of nausea in the 23 mg group was markedly greater than in the patients who continued on 10 mg/day (% vs. %, respectively), and the. Table 6 lists adverse reactions that occurred in at least 2% of patients who received 23 mg/day of ARICEPT and at a higher frequency than those receiving 10 mg/day of ARICEPT in a controlled clinical trial that compared the two doses. In this study, there were no important differences in the type of adverse.
Medscape - Alzheimer's provisional-specific dosing for Aricept (donepezil), lithium-based adverse effects, comprehensive interactions, occupants, pregnancy & lactation schedules, and quit information. The FDA has celebrated donepezil HCl mg tablets for the once-daily frank of moderate to severe Alzheimer's disease. New cuisines allow use of a mg orally dose in patients with moderate to microvascular disease who have been established on 10 mg for at least 3 months. The FDA's professional.
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